Abstract: Despite the fact that CO2 is a primary green-house gas, CO2 is abundant, inexpensive, non-flammable and attractive as an environmentally friendly reagent in organic chemistry.1 Thus, fixation of CO2 has received significant attention from the viewpoint of organic synthesis. Carboxylation is one such reaction. Reaction of carbon nucleophiles with CO2 is one of the most fundamental processes for CO2 fixation and is an attractive way to synthesize carboxylic acids. However, π orbitals in CO2 are filled and relatively low in energy and hence highly inert. Thus, the reaction of CO2 involves the use of high pressure or temperature, or both. But in the presence of transition metal (Ni, Pd), the carboxylation can be done in a mild and effective way.2 Among the transition metals, Ni is found to be best due to its high reactivity, low toxicity and low cost. Recently, Ni-catalyzed carboxylation has emerged as a useful tool for the same.3 The carboxylation reactions using CO2 giving importance to Ni-catalyzed transformations are planned in this presentation.


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